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N5315 Adv. Pathophysiology Hematologic System Core Concepts and Objectives with Advanced Organizers
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N5315 Advanced Pathophysiology Hematologic System Core Concepts and Objectives with Advanced Organizers
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N5315 Advanced Pathophysiology
Hematologic System
Core Concepts and Objectives with Advanced Organizers
Hemostasis
PLATELET PLUG FORMATION
Platelet Structure Function
Peripheral zone -Outer most portion of cell
-Cell membrane
-Made of phospholipids.
-Open cannicular system provides channels for substances produced by
platelets to be produces and releases.
-Phospholipid membrane provides a site for coag proteins and adhesive
proteins to bind. Also produces thromboxane A2 via arachidonic path.
-Contains platelet receptors which cause platelet adhesion and
aggregation.
Sol-gel zone -Middle layer
-Structural support of the cell.
Organelle Zone -Contains the organelles. The mitochondria, the dense tubular system
(stores ca...
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N5315 Adv. Pathophysiology Hematologic System Core Concepts and Objectives with Advanced Organizers
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