NURS 4380 PATHOPHYSIOLOGY,PHARMACOLOGY & PHYSICAL ASSESSMENT FINAL EXAM STUDY GUIDE Latest 2021
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Patho Pharm Final Review
NURS 4380 PATHOPHYSIOLOGY,PHARMACOLOGY &
PHYSICAL ASSESSMENT FINAL EXAM STUDY GUIDE Latest 2021/2022
Basics of Antibiotics (13)
1. Define selective toxicity as it applies to the general mechanisms by which antibiotics work against invading pathogens but not against host cells.
o Selective toxicity means that the drug interferes with necessary microbial biochemical processes. The pathogen is a prokaryote, while the host (us) is eukaryote, so their genetic makeup is different.
• Explain disruption of bacterial cell wall (Ex: Penicillin and cephalosporins)
➢ Prokaryotes (Bacteria) are encased in a rigid cell wall
➢ The protoplasm within this wall has a high concentration of solutes, making osmotic pressure within high
➢ Without this cell wall, bacteria would absorb water, swell, and then burst
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NURS 4380 PATHOPHYSIOLOGY,PHARMACOLOGY & PHYSICAL ASSESSMENT FINAL EXAM STUDY GUIDE Latest 2021/2022
NURS 4380 PATHOPHYSIOLOGY,PHARMACOLOGY & PHYSICAL ASSESSMENT FINAL EXAM STUDY GUIDE Latest 2021
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