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Distinguishing Critical, Beneficial, Neutral and Harmful Mutations
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Distinguishing Critical, Beneficial, Neutral and Harmful Mutations Uncovered in the Directed Evolution of a Yeast Membrane Receptor
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Abstract
We present a reversion analysis of mutations introduced during the directed
evolution of the yeast G-protein coupled receptor (GPCR) Ste2p to detect a peptide
biomarker of chronic kidney disease. Two mutated receptors are analyzed in this study.
Mutations acquired during directed evolution wer...
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Distinguishing Critical, Beneficial, Neutral and Harmful Mutations
Abstract
We present a reversion analysis of mutations introduced during the directed
evolution of the yeast G-protein coupled receptor (GPCR) Ste2p to detect a peptide
biomarker of chronic kidney disease. Two mutated recep...
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