PATHO PRACTICE QUIZ/PRACTICE QUIZ QUESTIONS & ANSWERS PATHOPHYSIOLOGY

WEEK ONE TOPIC: CELLULAR INJURY, ADAPTATION AND CELL DEATH

1.                   Which cellular organelle is responsible for energy production?

a.                   Nucleus

b.                   Mitochondria

c.                   Ribosomes

d.                   Endoplasmic reticulum Ans B

2.                   Movement of water across membranes following its concentration gradient occurs through

a.                   Facilitated diffusion

b.                   Active transport

c.                   Osmosis

d.                   Pinocytosis Ans C

3.                   Which molecule is the “energy currency” of the cell?

a.                   Sugar

b.                   Amino acids

c.                   ATP

d.                   GTP

Ans C

4.                   A 75-year-old female with Alzheimer’s disease has increased lipid peroxidation secondary to free-radical production. Lipid peroxidation results in

a.                   Organelle membrane reconstruction

b.                   Increased lipid transportation

c.                   Increased protein synthesis

d.                   Cell membrane damage Ans D

5.                   In response to an increased workload, myocardial cells will

a.                   Increase in size

b.                   Decrease in length

c.                   Increase in excitability

d.                   Increase in number Ans A

6.                   A 40-year-old female is undergoing treatment for cervical cancer. Which cellular change is most likely to be associated with her cancer?

a.                   Metaplasia

b.                   Atrophy

c.                   Hypertrophy

d.                   Dysplasia Ans D

7.                   A 50-year-old male with a 30-year history of smoking is examined for a respiratory problem. Examination of his airway (bronchi) reveals that stratified squamous epithelial cells have replaced the normal columnar ciliated epithelium. The type of cellular adaptation seen is called?

a.                   Hypertrophy

b.                   Hyperplasia

c.                   Metaplasia

d.                   Dysplasia Ans C

8.                   Which of the following is an active cell death process?

a.                   Necrosis

b.                   Lysis

c.                   Apoptosis

d.                   Senescence Ans C

9.                   You have been invited by a leading research laboratory to help develop targeted anti-cancer drugs which activate the intrinsic apoptotic pathway. Which of the following you will choose as your drug target?

a.                   Nucleolus

b.                   Mitochondria

c.                   Lysosomes

d.                   Microtubules B

10.               In which of the following situations would cells die by necrosis, not apoptosis?

a.                   Virus infected cells

b.                   Developing neurones which fail to make profitable connections with other cells

c.                   Heart muscle cells damaged by oxygen depletion following cardiac infarction

d.                   Cells with damaged DNA which cannot be repaired Ans C

WEEK 2 - TOPIC: INFLAMMATION & REPAIR

1.                   What is a purpose of the inflammatory process?

a.                   to provide specific responses toward antigens

b.                   to lyse cell membranes of microorganisms

c.                   to prevent infection of the injured tissue

d.                   to create immunity against subsequent tissue injury Ans C