PHARM MIDTERM STUDY GUIDE CORRECT QUESTIONS AND ANSWERS

PHARM MIDTERM STUDY GUIDE

CORRECT QUESTIONS AND ANSWERS

Chapter 2. Review of Basic Principles of Pharmacology

1.      A patient’s nutritional intake and laboratory results reflect hypoalbuminemia. This is critical to prescribing because:

Distribution of drugs to target tissue may be affected.

2.  Drugs that have a significant first-pass effect:

Are rapidly metabolized by the liver and may have little if any desired action 3.The route of excretion of a volatile drug will likely be the:

Lungs

4.  Medroxyprogesterone (Depo Provera) is prescribed intramuscularly (IM) to create a storage reservoir

Increase the length of time a drug is available and active

5.  The NP chooses to give cephalexin every 8 hours based on knowledge of the drug’s: Biological half-life

6.  Azithromycin dosing requires that the first day’s dosage be twice those of the other 4 days of the prescription. This is considered a loading dose. A loading dose:

Rapidly achieves drug levels in the therapeutic range

7.  The point in time on the drug concentration curve that indicates the first sign of a therapeutic effect is the:

Onset of action

8.  Phenytoin requires that a trough level be drawn. Peak and trough levels are done: To determine if a drug is in the therapeutic range

9.  A laboratory result indicates that the peak level for a drug is above the minimum toxic concentration. This means that the:

Concentration will produce an adverse response

10.  Drugs that are receptor agonists may demonstrate what property? Desensitization or downregulation with continuous use