Purple Book - Part II (Mood/Anxiety Disorders and Schizophrenia) Solved 100%

Purple Book - Part II (Mood/Anxiety Disorders and Schizophrenia) Solved 100%

What is the most common psychiatric illness? {{Ans- Mood disorders

What are the 5 theories of depression?

{{Ans- Object loss theory (psychodynamic)

Aggression-Turned-Inward Theory (psychodynamic)

Cognitive theory

Learned helplessness-hopelessness theory

Biological theory

What 2 psychodynamic theories attribute depression to loss of maternal figure (death, illness, lack of emotional availability)

{{Ans- Object loss theory

Aggression-Turned-Inward theory (Freud)

The diathesis-stress model of depression refers to what type of theory? {{Ans- Cognitive theory

The theory that assumes depression is due to lack of control over life events and powerlessness, where the person becomes passive is

{{Ans- Learned helplessness-hopelessness theory (Seligman)

What are 5 biological theories of depression?

{{Ans- Genetic predisposition

Endocrine dysfunction

Neurotransmitter abnormalities

Structural brain changes

Chronobiological theory

What is the strongest predictor of depression? {{Ans- Having a depressed parent (3x more likely)

A person who has an earlier age of onset and more severe symptoms of depression is likely to have what etiology? {{Ans- Genetic

What is the theory of depression related to endocrine dysfunction?

{{Ans- Abnormal stress response related to HPA dysregulation

What are 4 endocrine abnormalities to depressed patients have?

{{Ans- Hyperactive HPA system

Elevated cortisol levels

Proinflammatory cytokine activation

Positive DST (nonspecfic)

What are 4 abnormalities of neurotransmitter function in depression?

{{Ans- Low neurotransmitters (DA, 5HT, NE)

Low tryptophan (5HT precursor)

Low 5HT1AA (5HT metabolite)

Receptor sensitivity and low density

What 2 brain structure abnormalities are found in depression?

{{Ans- decreased hippocampus