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NR 507 Midterm Specific StudyGuide (Spring 2018) | Complete Solution
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Epigenetics
- Defects in the encoding of histone-modifying proteins (Chp 6 and 12 wk 1)
- Epigenetics and (45) its role on human development. (chp 6)
- Totipotent cells
- Angelman syndrome? – loss of the maternal copy of UBE3A
Cellular Proliferation
- 5-Azacytidine and the(44) treatment of cancer (Chap 6 & Chp 12- wk 1)
- the role of inactive MLH1 in the development of some forms of inherited colon cancer.
- Effects of ethanol on neural stem cells ability to differentiate into functional neurons (chap 13,wk 1) (Chap 2
- Inflammation as an etiology for cancer-note conditions in which this may occur
Cancer
- In terms of epigenetic modifications, the role of environmental stressors associated with development of cancer.
Defects in Mechanism of Defense
- Hemolytic defects in the newborn
- Understand the meaning of infectivity ( chap 10 )
- Most effective treatment for HIV-
- Defected cells of HIV
- Signs of T-Lymphocyte deficiency
Pulmonary Alterations
- Pulmonary function tests
- Relationship of lung compliance and (46) residual volume
- Shifts in the oxyhemoglobin dissociation- (chap 3, 17, 34)
- CO2 transport in the blood ( chap 34)
- Characteristics of alveoli-
- Arterial perfusion pressure in the lung base and
- alveolar gas pressure in the lung base
- How do determine the partial pressure of oxygen given the percentage of oxygen in the air and
- (23) the barometric pressure
- Results of increased work of breathing Know terms: Chapter 34
- Vital capacity (VC),
- Total lung capacity
- Functional capacity-
- Residual volume (RV)
- Functional residual capacity (FRC) –
Renal Alterations
- Types of nephrons and (48) their functions (chap 37)
- Overall renal physiology-
- Substances that are actively secreted by the renal tubules (Chap39)
- Activation of the renin-angiotensin system
- Glomerular filtration rate- clearance
- Mesangial cells-
- Renal system anatomy
- Why plasma proteins should be absent from the urine-
- Effects of urinary tract obstruction- hydronephrosis and a
- (39) decreased glomerular filtration rate
- Effect of urinary retention
- Epispadias
- Glomerulonephritis- ( chap 38)
- Nephrotic syndrome- ( chap 38)
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[Solved] NR 507 Midterm Specific StudyGuide (Spring 2018) | Complete Solution
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Epigenetics
1.Defects in the encoding of histone-modifying proteins (Chp 6 and 12 wk 1)
Histone modification (e.g., histone acetylation and deacetylation, alterations in chromatin): Chromatin compaction and organization help to regulate gene expression, determining and maintaining cell identity. Chromatin structure must be controlled in self-renewing and differentiated cells in cell renewal systems. For example, there are differences in chromatin structure in stem cells and terminally differentiated cells
are chemical modifications of ...
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