LAT LABORATORY ANIMAL TECHNICIAN WITH COMPLETE SOLUTIONS

LAT LABORATORY ANIMAL TECHNICIAN WITH COMPLETE SOLUTIONS

U.S. Government provides approximately how much in research/development funds spent by 
college and university? - 2/3
What information is important on grant applications to request funds? - Detailed description of 
research goals, scientific basis of study, and review of relevant literature and all procedures to 
be performed
What is the difference between NIH & NSF? - NIH: primary granting agency: academia, federal 
agencies, biomedical research 
NSF: Basic research in math, medicine, and biology
The USDA stands for what? - United States Department of Agriculture
The USDA is responsible for what? - Enforces and amends AWA
Auction, sale, exhibit, transport, breeding, or conduct of research with animals
Animals exempt from AWA
Research institutions mst register with
Supply annual reports
Inspection records through the FOIA
Unscheduled inspection once per year
What does the FOIA stand for? - Freedom of Information Act - provides the USDA's inspection 
records
What is the Public Health Service Policy? - Institutions which receive funding from PHS and NIH 
must follow these guidelines, requires filing of an Amimal Welfare Assurance document that 
demonstrates the institution is following the Guid, PHS policy, AWA, and any other applicable laws
The FDA has many responsibilites including: - Assures that new drugs and medical devices are 
safe and effective before approved for use in humans
Monitors drug approval
Includes human, and veterinary drugs, food, and medical devices
Requires that effectiveness be demonstrated through well controlled investigations
What is GLP? - Good Laboratory Practices
Established in 1978 with implementation of laboratory audits and inspection programs
Details requirements for QA and SOPs
What is the importance of importation and transportations regulations? - For the protection of 
humans and environment from potential disease carrying organisms
Which agencies control importation? - CDC, USDA, and US Fish & Wildlife Service
Institutional polices are established for: - facility operations
care and use procedures
veterinary support
physical plant
Standard operating procedures relate to: - wall aspects of animal care and support
personnel management
health surveillance of animals and personnel
equipment
investigators
What are the functions of IACUCs and who mandates? - mandated by AWA, PHS policy, and the 
Guide
Review and approve protocols for animal use
Review animal use program and perform animal facilities inspections at least every 6 months
What has to happen before animal research can begin? - principal investigator provides written 
details of how animals will be used in the research project
IACUC must review all protocols using animals and must approve all protocols before any animal 
research can begin
What does the IACUC determine? - Can deny permission ro start a project
can stop a research peoject
Ensures compliance with regulations
Reviews complete protocols at least every 3 years; reviews updates to protocols yearly
What is the AAALAC, International? - Association for Assessment and Accreditation of Laboratory 
Animal Care, International
Non-profit organization that provides a mechanism for peer review of animal care and use 
programs by scientific community
Detailed application with information on facilities, procedures, programs, and research animals to 
use
Annual report must be submitted to AAALAC on status of animal care program
Site inspection and program evaluation every 3 years
Why is it important to keep accurate, up-to-date records? - Determine if procedures are followed 
according to established standards
Determine whether environmental controls are properly maintained
Improve facility efficiency and effectivness
What is PHS Policy? - All assurance records related directlyto grant applications, research 
proposals, and changes of research activities > 3yrs after completion
Centralized - Serves all the institution's animal care needs; 1 director for entire institution; All 
personnel associated with the animal facility; All other purchases, per diem, depreciation, 
inventories, operational costs, and supplies